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Antigenic Specificity | PAM16 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.9 mg/mL |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total PAM16 protein. This gene encodes a mitochondrial protein involved in granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling. This protein also plays a role in the import of nuclear-encoded mitochondrial proteins into the mitochondrial matrix and may be important in reactive oxygen species (ROS) homeostasis. Mutations in this gene cause Megarbane-Dagher-Melike type spondylometaphyseal dysplasia, an early lethal skeletal dysplasia characterized by short stature, developmental delay and other skeletal abnormalities. |
Immunogen | Immunogen: Fusion protein of human PAM16 Immunogen Type: Peptide |
Other Names | [TIM16; MAGMAS; SMDMDM; TIMM16; CGI-136] |
Gene, Accession # | [PAM16], Gene ID: 51025, NCBI: NP_057153.8, UniProt: Q9Y3D7 |
Catalog # | MBS9430413 |
Price | $255 |
Order / More Info | PAM16 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |