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Antigenic Specificity | PICK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PICK1 antibody detects endogenous levels of total PICK1. Description: Protein interacting with C kinase 1 (PICK1) is a PDZ-domain containing protein that is located in the perinuclear region and is phosphorylated in response to PKC? activation. PKC?, which is essential for the regulation of proliferation and differentiation in numerous cell types, contains within its catalytic region a PDZ-binding domain that is absent from other PKC isoforms. Mutation of the PICK1 PDZ domain inhibits the binding of PICK1 to PKC?. PICK1 also interacts with the carboxy terminus of a-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA) receptor, a neurotransmitter receptor located at excitatory synapses, suggesting that PICK1 plays a role i |
Immunogen | Immunogen: A synthetic peptide of human PICK1 Subcellular Location: Cytoplasm > Perinuclear Region. Cell Junction > Synapse. Also present at excitatory synapses. Tissue Specificity: Ubiquitous. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (93%), Horse (100%), Sheep (100%), Rabbit (87%), Dog (100%), Chicken (100%), Xenopus (87%) |
Other Names | [dJ1039K5; MGC15204; OTTHUMP00000028509; PICK 1; Pick1; PICK1_HUMAN; PRKCA binding protein; PRKCA-binding protein; PRKCABP; Protein interacting with C kinase 1; Protein interacting with PRKCA; Protein interacting with PRKCA 1; Protein kinase C alpha binding protein; Protein kinase C-alpha-binding protein; Protein that interacts with C kinase 1] |
Gene, Accession # | [PICK1], Gene ID: 9463, NCBI: NP_001034672.1, UniProt: Q9NRD5 |
Catalog # | MBS9607095 |
Price | $240, $280 |
Order / More Info | PICK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |