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Antigenic Specificity | TLR6 (C-term), 393-423 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Flow Cytometry (FC/FACS), ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TLR6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 393-423 amino acids from the C-terminal region of human TLR6. TLR6, a Type I membrane protein that belongs to the Toll-like rceptor family, participates in the innate immune response to Gram-positive bacteria and fungi. It acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. The protein recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. It binds to TLR2 via their respective extracellular domains, and to MyD88 via t |
Immunogen | n/a |
Other Names | [Toll-like receptor 6; CD286; TLR6] |
Gene, Accession # | [TLR6], Gene ID: 10333, NCBI: NP_006059.2, UniProt: Q9Y2C9 |
Catalog # | MBS9204052 |
Price | $165, $370 |
Order / More Info | TLR6 (C-term), 393-423 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bulut, Y., et al., J. Immunol. 167(2):987-994 (2001). Takeuchi, O., et al., Gene 231 (1-2), 59-65 (1999). |