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Antigenic Specificity | PAF-R |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PAF-R Polyclonal Antibody detects endogenous levels of PAF-R protein. PTAFR (platelet activating factor receptor) encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes. Binding of PAF to the PAF-receptor (PAFR) stimulates numerous signal transduction pathways including phospholipase C, D, A2, mitogen-activated protein kinases (MAPKs), and the phosphatidylinositol-calcium second messenger system. Following PAFR activation, |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human PAF-R at AA range: 170-250 |
Other Names | [Rabbit PAF-R; PTAFR; PAFR; Platelet-activating factor receptor; PAF-R; PAFr] |
Gene, Accession # | [PAF-R], Gene ID: 5724, NCBI: NP_000943.1, UniProt: P25105 |
Catalog # | MBS9706511 |
Price | $130, $220, $325 |
Order / More Info | PAF-R Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |