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Antigenic Specificity | WHSC1L1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: WHSC1L1 antibody detects endogenous levels of total WHSC1L1. Description: This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. The function of the protein has not been determined. Two alternatively spliced variants have been described.Function: Histone methyltransferase. Preferentially methylates 'Lys-4' and 'Lys-27' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression.Subunit Structure: Interacts with BRD4.Similarity: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltr |
Immunogen | Immunogen: A synthesized peptide derived from human WHSC1L1 Subcellular Location: Nucleus. Chromosome. Tissue Specificity: Highly expressed in brain, heart and skeletal muscle. Expressed at lower level in liver and lung. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (92%), Horse (83%), Sheep (100%), Rabbit (100%), Dog (100%) |
Other Names | [DKFZp667H044; FLJ20353; Histone lysine N methyltransferase NSD3; Histone-lysine N-methyltransferase NSD3; MGC126766; MGC142029; NSD 3; NSD3_HUMAN; Nuclear set domain containing 3; Nuclear SET domain containing protein 3; Nuclear SET domain-containing protein 3; pp14328; Protein whistle; Whistle; WHSC1 like protein 1; WHSC1-like 1 isoform 9 with methyltransferase activity to lysine; WHSC1-like protein 1; WHSC1L1; WHSC1L1 protein; Wolf Hirschhorn syndrome candidate 1 like 1; Wolf-Hirschhorn syndrome candidate 1-like protein 1] |
Gene, Accession # | [WHSC1L1], Gene ID: 54904, NCBI: NP_060248.2, UniProt: Q9BZ95 |
Catalog # | MBS9608047 |
Price | $240, $280 |
Order / More Info | WHSC1L1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |