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Antigenic Specificity | Human M-CSF |
Clone | [3V17] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Neutr |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | M-CSF, also known as CSF1, is a four-alpha-helicalbundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. M-CSF is also essential for the survival and proliferation of osteoclast progenitors. M-CSF-also primes and enhances macrophage killing of tumor cells and microorganisms, regulates the release of cytokines and other inflammatory modulators from macrophages, and stimulates pinocytosis. MCSF increases during pregnancy to support implantation and growth of the decidua and placenta. Sources of M-CSF include fibroblasts, activated macrophages, endometrial secretory epithelium, bone marrow stromal cells and activated endothelial cells. The MCSF receptor (cfms) transduces its pleotropic effects |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of M-CSF. |
Other Names | [CSF1; MCSF; CSF-1], [CSF1; CSF1; MCSF; CSF-1; CSF-1; M-CSF; MCSF] |
Gene, Accession # | [M-CSF], Gene ID: 1435, NCBI: NP_000748.3, UniProt: P09603 |
Catalog # | MBS690427 |
Price | $490 |
Order / More Info | Human M-CSF Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |