Phospho-Afadin (Ser1799) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-Afadin (Ser1799) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-Afadin (Ser1799) antibody detects endogenous levels of Afadin. Function: Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin-and actin-filament-binding protein that connects nectin to the actin cytoskeleton.Subunit Structure: Homodimer. Interacts with F-actin, nectin and NECTIN3. Essential for the association of nectin and E-cadherin. Isoform 1/s-afadin does not interact with F-actin. Interacts with ZO-1 and occludin, but probably in an indirect manner. Interacts with RIT1 and RIT2 (By similarity). Interacts with NRXN1 and BCR.Similarity: The PDZ/DHR domai |
| Immunogen | Immunogen: A synthesized peptide derived from human Afadin around the phosphorylation site of Ser1799. Subcellular Location: Cell Junction > Adherens Junction. Not found at cell-matrix AJs. Predicted Cross Reactivity: Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Bovine (92%), Sheep (92%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (92%) |
| Other Names | [AF6; AFAD_HUMAN; Afadin; ALL1-fused gene from chromosome 6 protein; Mllt4; Protein Af-6; Protein AF6] |
| Gene, Accession # | [AFDN], Gene ID: 4301, NCBI: NP_001035089.1, UniProt: P55196 |
| Catalog # | MBS9600643 |
| Price | $240, $280 |
| Order / More Info | Phospho-Afadin (Ser1799) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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