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Antigenic Specificity | PTK7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Protein-tyrosine kinases (PTKs) play important roles in regulating cell proliferation and differentiation during development. One member of the PTK family, PTK7, has been suggested to regulate the planar cell polarity (PCP) pathway in vertebrates and may play a role in neural convergent extension and neural tube closure. PTK7 has also been implicated in the development of cancer. Loss of PTK7 expression was seen in several melanoma cell lines and biopsies. Conversely, high-throughput analysis of acute myeloid leukemia samples showed an increased level of PTK7 expression compared to normal bone marrow and purified CD34+ cells. Multiple isoforms of PTK7 are known to exist. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 18 amino acid peptide from near the carboxy terminus of human PTK7. |
Other Names | [Protein tyrosine Kinase 7, colon carcinoma kinase-4, CCK-4] |
Gene, Accession # | [PTK7], Gene ID: 5754, NCBI: AAH71557 |
Catalog # | MBS9401955 |
Price | $320 |
Order / More Info | PTK7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |