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Antigenic Specificity | Human Centrin-2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Plays a fundamental role in microtubule organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CCP110. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with RAD23B appears to stabilize XPC. In vitro, stimulates DNA binding of the XPC:RAD23B dimer. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged D |
Immunogen | Immunogen: Recombinant human Centrin-2 protein (1-172aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-27794 |
Other Names | [Caltractin isoform 1; CETN2; CALT; CEN2], [CETN2; CETN2; CALT; CEN2; CALT; CEN2] |
Gene, Accession # | [CETN2], Gene ID: 1069, NCBI: NP_004335.1, UniProt: P41208 |
Catalog # | MBS1492232 |
Price | $120, $160 |
Order / More Info | Human Centrin-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |