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Antigenic Specificity | CD40/TNFRSF5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | dog, Gerbil, human, mouse, rat |
Isotype | n/a |
Format | serum |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Formalin/Paraffin, Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD40 and its ligand CD154 are members of the tumor necrosis factor receptor (TNFR) and TNF families, respectively, that play key roles in signaling pathways mediating cell growth, survival and differentiation in B-lymphocytes. The CD40 receptor is a 45-50 kDa glycoprotein and is expressed on the surface of B-lymphocytes, some activated T-cells, monocytes, follicular dendritic cells, basal epithelial cells, and in some epithelial and non-epithelial carcinomas. The functions of CD40 have been most extensively studied in B-cells. Several distinct structural motifs in the CD40 cytoplasmic domain regaulate various CD40 signaling pathways. A major CD40 signaling pathway activated from CD154 ligand binding is the canonical pathway to the transcrip |
Immunogen | Immunogen Information: A recombinant protein containing the short cytoplasmic domain of the human CD40 molecule was used as immunogen for this antibody |
Other Names | [CD40; TNFRSF5; B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40; to CD40/TNFRSF5; CD40/TNFRSF5; CD40/TNFRSF5], [CD40; CD40; p50; Bp50; CDW40; TNFRSF5; TNFRSF5] |
Gene, Accession # | [CD40], Gene ID: 958, NCBI: P25942.1, UniProt: P25942 |
Catalog # | MBS668590 |
Price | $270 |
Order / More Info | CD40/TNFRSF5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |