PTEN Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | PTEN |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | rat. predicted to work with: human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN(PTEN) detection. Tested with WB in Human;Rat. Background: PTEN is also known as BZS, DEC, CWS1, GLM2, MHAM, TEP1, PTEN1. It is mapped to 10q23.3. This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide subs |
| Immunogen | Immunogen: E Coli-derived human PTEN recombinant protein (Position: E91-V403). Human PTEN shares 99.7% amino acid (aa) sequence identity with mouse PTEN. Ig Type: Rabbit IgG |
| Other Names | [Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; 10q23del; Bannayan Zonana syndrome; BZS; DEC; GLM2; ITGA 2; MGC11227; MHAM; MMAC 1; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; Multiple hamartoma (Cowden syndrome); Mutated in multiple advanced cancers 1; Mutated in Mutiple Advanced Cancers 1; Phosphatase and Tensin Homolog; Phosphatase and tensin like protein; Phosphatidylinositol 345 trisphosphate 3 phosphatase and dual specificity protein phosphatase PTEN; Phosphatidylinositol 345 trisphosphate 3 phosphatase; Phosphatidylinositol-3,4,5-trisphosphate 3 phosphatase and dual-specificity protein phosphatase PTEN; Platelet antigen BR; PTEN 1; Pten; PTEN_HUMAN; PTEN1; Tensin homolog; TEP 1; TEP1; VLA 2 Receptor Alpha Subunit; phosphatase and tensin homolog], [PTEN; PTEN; BZS; DEC; CWS1; GLM2; MHAM; TEP1; MMAC1; PTEN1; 10q23del; MMAC1; TEP1] |
| Gene, Accession # | [PTEN], Gene ID: 5728, NCBI: NP_000305.3, UniProt: P60484 |
| Catalog # | MBS177889 |
| Price | $280 |
| Order / More Info | PTEN Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Lee, J.-O., Yang, H., Georgescu, M.-M., Di Cristofano, A., Maehama, T., Shi, Y., Dixon, J. E., Pandolfi, P., Pavletich, N. P. Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. Cell 99: 323-334, 1999. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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