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Antigenic Specificity | NR2C2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NR2C2 antibody detects endogenous levels of total NR2C2. Function: Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Plays a fundamental role in early embryo |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus. Tissue Specificity: Transiently repressed during the meiotic phase of spermatogenesis. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Pig (92%), Bovine (82%), Horse (83%), Sheep (100%), Rabbit (100%), Dog (83%), Chicken (100%) |
Other Names | [hTAK1; Nr2c2; NR2C2_HUMAN; Nuclear hormone receptor TR4; Nuclear receptor subfamily 2 group C member 2; Orphan nuclear receptor TAK1; Orphan nuclear receptor TR4; TAK1; Testicular nuclear receptor 4; Testicular receptor 4; TR2R1; TR4; TR4 nuclear hormone receptor] |
Gene, Accession # | [NR2C2], Gene ID: 7182, NCBI: NP_001278623.1, UniProt: P49116 |
Catalog # | MBS9603757 |
Price | $240, $280 |
Order / More Info | NR2C2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |