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Antigenic Specificity | Phospho-EIF2S1-S51 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | IgG |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]). |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding S51 of human eIF2a |
Other Names | [EIF-2; EIF-2A; EIF-2alpha; EIF2; EIF2A] |
Gene, Accession # | [EIF2S1-S51], Gene ID: 1965, NCBI: P05198.3, UniProt: P05198 |
Catalog # | MBS9132860 |
Price | $275, $430, $655 |
Order / More Info | Phospho-EIF2S1-S51 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |