NSG1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNSG1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: NSG1 antibody detects endogenous levels of total NSG1. Function: Plays a role in the recycling mechanism in neurons of multiple receptors, including AMPAR, APP and L1CAM and acts at the level of early endosomes to promote sorting of receptors toward a recycling pathway. Regulates sorting and recycling of GRIA2 through interaction with GRIP1 and then contributes to the regulation of synaptic transmission and plasticity by affecting the recycling and targeting of AMPA receptors to the synapse (By similarity). Is required for faithful sorting of L1CAM to axons by facilitating trafficking from somatodendritic early endosome or the recycling endosome (By similarity). In an other hand, induces apoptosis via the activation of CASP3 in
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Golgi Apparatus Membrane. Tissue Specificity: Up-regulated by TP53 after DNA damage (PubMed:20599942). Up-regulated by genotoxic stress (PubMed:20878061). Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (82%), Bovine (91%), Horse (91%), Sheep (91%), Rabbit (100%), Dog (100%)
Other Names[Brain neuron cytoplasmic protein 1; Brain specific mRNA b; Bsmrb; Neuron-specific gene family member 1; Neuron-specific protein family member 1; NSG1; NSG1_HUMAN; PEP1]
Gene, Accession #[NSG1], Gene ID: 27065, NCBI: NP_001035190.1, UniProt: P42857
Catalog #MBS9605696
Price$240, $280
Order / More InfoNSG1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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