Musk Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMusk
Clone[1429CT456.173.44]
Host SpeciesMouse
Reactive Speciesmouse, rat
IsotypeIgG1,k
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
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DescriptionThis mouse Musk antibody is generated from a mouse immunized with recombinant protein from mouse Musk. Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle. Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of MUSK, the kinase of the complex. The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes including the specific expression of genes in subsynaptic nuclei, the reorganization of the actin cytoskeleton and the clustering of the acetylcholine receptors (AChR) in the postsynaptic membrane. May regulate A
Immunogenn/a
Other Names[Muscle; skeletal receptor tyrosine-protein kinase; Muscle-specific tyrosine-protein kinase receptor; MuSK; Muscle-specific kinase receptor; Musk; Nsk2]
Gene, Accession #[Musk], Gene ID: 18198, NCBI: NP_001032205.1, UniProt: Q61006
Catalog #MBS9200303
Price$165, $370
Order / More InfoMusk Antibody from MYBIOSOURCE INC.
Product Specific ReferencesCaruso A.,et al.Submitted (OCT-1995) to the EMBL/GenBank/DDBJ databases. Ganju P.,et al.Oncogene 11:281-290(1995). DeChiara T.M.,et al.Cell 85:501-512(1996). Glass D.J.,et al.Cell 85:513-523(1996). Lin W.,et al.Nature 410:1057-1064(2001).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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