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Antigenic Specificity | E Cadherin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.025 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | E-cadherin is a calcium-regulated adhesion molecule expressed in most normal epithelial tissues. It is localized on the surfaces of epithelial cells in regions of cell-cell contact known as adherens junctions. The E-cadherin gene is located on chromosome 16q22.1. E-cadherin is associated with gland formation, stratification, and epithelial polarization. Besides its role in normal cells, this highly conserved gene can play a major role in malignant cell transformation, and especially in tumor development and progression. Selective loss of E-cadherin can cause dedifferentiation and invasiveness in human carcinomas, leading E-cadherin to be classified as a tumor suppressor. |
Immunogen | Immunogen Information: A partial length recombinant E-cadherin protein (amino acids 438-556) was used as the immunogen for this antibody. |
Other Names | [CDH1; CDHE; UVO; CAM 120/80; E-cadherin; Epithelial cadherin; Uvomorulin; to E Cadherin; E Cadherin; E Cadherin], [CDH1; CDH1; UVO; CDHE; ECAD; LCAM; Arc-1; CD324; CDHE; UVO; E-cadherin] |
Gene, Accession # | Gene ID: 999, NCBI: P12830.3, UniProt: P12830 |
Catalog # | MBS668635 |
Price | $140, $270 |
Order / More Info | E Cadherin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |