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Antigenic Specificity | RUVBL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total RUVBL1 protein. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human RUVBL1. |
Other Names | [RVB1; TIH1; ECP54; TIP49; INO80H] |
Gene, Accession # | [RUVBL1], Gene ID: 8607, NCBI: NP_003698.1, UniProt: Q9Y265 |
Catalog # | MBS9412464 |
Price | $255 |
Order / More Info | RUVBL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |