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Antigenic Specificity | PDK1 |
Clone | [4A11] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 0.05 mL |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Kinase that plays a key role in regulation of glucose and fatty acidmetabolism and homeostasis via phosphorylation of the pyruvatedehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvatedehydrogenase activity, and thereby regulates metabolite flux throughthe tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. |
Immunogen | Immunogen: Purified recombinant fragment of human PDK1 expressed in E. coli. Conjugation: Unconjugated |
Other Names | [Rabbit (IgG) to Human PDK1; PDK1; PDHK; PDH kinase 1; PDHK1] |
Gene, Accession # | [PDK1], Gene ID: 5163, NCBI: NP_002601.1, UniProt: Q15118 |
Catalog # | MBS2401634 |
Price | $530 |
Order / More Info | PDK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |