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Antigenic Specificity | Human CD273/PD-L2 |
Clone | [24F.10C12] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, kappa |
Format | phycoerythrin (PE) conjugate |
Size | 20 tests, 50 tests, 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions. |
Immunogen | n/a |
Other Names | [B7DC; CD273; PDCD1L2; PDL2] |
Gene, Accession # | [CD273/PD-L2], Gene ID: 80380, NCBI: NP_079515.2, UniProt: Q9BQ51 |
Catalog # | MBS2559226 |
Price | $100, $125, $165 |
Order / More Info | Human CD273/PD-L2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |