Human Tyrosyl-DNA phosphodiesterase 1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Tyrosyl-DNA phosphodiesterase 1 |
| Clone | [PAT1F2AT] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG2b k |
| Format | Protein G purified |
| Size | 0.005 mg, 0.02 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Introduction: TDP1 belongs to the phospholipase D family and contains two PLD phosphodiesterase domains. TDP1 is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. TDP1 may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. Mutations in the TDP1 gene are linked to the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). |
| Immunogen | Immunogen: Anti-human TDP1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TDP1 amino acids 1-298 purified from E Coli. |
| Other Names | [TDP1; Tyrosyl-DNA phosphodiesterase 1, Mouse Human; Tyrosyl-DNA phosphodiesterase 1; Tyr-DNA phosphodiesterase 1; TDP1; FLJ11090; MGC104252], [TDP1; TDP1; Tyr-DNA phosphodiesterase 1] |
| Gene, Accession # | [TDP1], Gene ID: 55775, NCBI: NP_001008744.1 |
| Catalog # | MBS140331 |
| Price | $140, $205, $505 |
| Order / More Info | Human Tyrosyl-DNA phosphodiesterase 1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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