IKB alpha (IKBA), 1-30 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | IKB alpha (IKBA), 1-30 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This IKB alpha (IKBA) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from human IKB alpha (IKBA). NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T |
| Immunogen | n/a |
| Other Names | [NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3; NFKBIA; IKBA; MAD3; NFKBI] |
| Gene, Accession # | [NFKBIA], Gene ID: 4792, NCBI: NP_065390.1, UniProt: P25963 |
| Catalog # | MBS9207043 |
| Price | $165, $370 |
| Order / More Info | IKB alpha (IKBA), 1-30 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Miskolci, V., et al., Arch. Biochem. Biophys. 417(1):44-52 (2003). Kim, Y.S., et al., J. Biol. Chem. 278(31):28462-28469 (2003). Parcellier, A., et al., Mol. Cell. Biol. 23(16):5790-5802 (2003). Takada, Y., et al., J. Biol. Chem. 278(26):24233-24241 (2003). Place, R.F., et al., J. Cell. Physiol. 195(3):470-478 (2003). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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