Human CD266 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Human CD266 |
| Clone | [ITEM-4] |
| Host Species | Mouse |
| Reactive Species | mouse, rat |
| Isotype | IgG2b |
| Format | unconjugated |
| Size | 0.2 mg |
| Concentration | IgG concentration 1.0mg/ml |
| Applications | Immunohistology Frozen, Flow cytometry (FC/FACS), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mouse anti Human CD266 antibody, clone ITEM-4 recognizes human CD266, otherwise known as Fn14/TWEAK Receptor, a 14kDa type I transmembrane glycoprotein and member of the tumour necrosis factor receptor superfamily (TNFRSF12A) expressed by a variety of tissues, including the heart, lung and kidney, and at elevated levels by human brain and liver tumours. The interaction between CD266 and its ligand CD255 (TWEAK), induces the proliferation and migration of endothelial cells and also angiogenesis, and studies have shown that CD255-induced apoptosis of some tumour cell lines is mediated by CD266 (Nakayama et al. 2003). Mouse anti Human CD266 antibody, clone ITEM-4 is cross-reactive with mouse CD266, and also with Rat-1 cells in flow cytometry. |
| Immunogen | Immunogen: Human CD266 transfected P815 cells Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the P3U1 mouse myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Human |
| Other Names | [tumor necrosis factor receptor superfamily member 12A; Tumor necrosis factor receptor superfamily member 12A; tumor necrosis factor receptor superfamily member 12A; FGF-inducible 14; fibroblast growth factor-inducible immediate-early response protein 14; tweak-receptor; type I transmembrane protein Fn14; tumor necrosis factor receptor superfamily, member 12A; Fibroblast growth factor-inducible immediate-early response protein 14; FGF-inducible 14; Tweak-receptor; TweakR; CD_antigen: CD266], [TNFRSF12A; TNFRSF12A; FN14; CD266; TWEAKR; FN14; FGF-inducible 14; TweakR] |
| Gene, Accession # | [CD266], Gene ID: 51330, NCBI: NP_057723.1, UniProt: Q9NP84 |
| Catalog # | MBS224691 |
| Price | $430 |
| Order / More Info | Human CD266 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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