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Antigenic Specificity | BMPR1A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mg |
Concentration | 0.5 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Overview: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.Structure: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. Contains 1 GS domain. Contains 1 protein kinase domain.Expression: Highly expressed in skeletal muscle. |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 460-510 on human Bone morphogenetic protein receptor type-1A. Determinant: Mid-region Conjugation: Unconjugated |
Other Names | [Affinity Purified Bone morphogenetic protein receptor type-1A; Activin A receptor type II like kinase 3; Activin receptor like kinase 3; ACVRLK 3; ALK 3; BMP type-1A receptor; BMPR 1A; Bmpr; Bone morphogenetic protein receptor type-1A; BR1a; CD292; Serine threonine protein kinase receptor R5; SKR5; zBMPR IA] |
Gene, Accession # | [BMPR1A], Gene ID: 604, NCBI: NP_001124317, UniProt: P36894 |
Catalog # | MBS5400351 |
Price | $390 |
Order / More Info | BMPR1A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |