Fc gamma receptor III [3G8] Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Fc gamma receptor III [3G8] |
| Clone | [3G8] |
| Host Species | Rabbit |
| Reactive Species | human, chimpanzee, baboon, cynomolgus, rhesus, pigtailed macaque, Capuchin monkey, squirrel monkey, Sooty Mangabey, Cotton-topped tamarin, marmoset |
| Isotype | IgG, kappa |
| Format | Protein A purified |
| Size | 0.2 mg |
| Concentration | 1 mg/ml |
| Applications | Flow Cytometry (FC/FACS), Surface Plasmon Resonance (SPR), Depletion, Immunoprecipitation (IP), Immunohistochemistry (IHC), Block (BL) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: 3G8 binds to CD16 at an epitope which is not the IgG-binding site. This antibody cannot distinguish between CD16a transmembrane isoform found on the surface of NK cells and macrophages (which can trigger the cytolytic response), and the GPI-linked CD16b isoform present on neutrophils or soluble CD16 found in the plasma. CD16 is the low affinity IgG receptor III and binds to aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis and ADCC (antibody-dependent cell-mediated cytotoxicity). Recombinant monoclonal antibody to Fc gamma receptor III. Manufactured using a proprietary Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 3G8. 3G8 was prepared by immunizing mice |
| Immunogen | Immunogen: 3G8 was prepared by immunizing mice with human PMN (polymorphonuclear leukocytes) cells. |
| Other Names | n/a |
| Gene, Accession # | NCBI: Q9ULV2, UniProt: Q9ULV2 |
| Catalog # | MBS488350 |
| Price | $425 |
| Order / More Info | Fc gamma receptor III [3G8] Antibody from MYBIOSOURCE INC. |
| Product Specific References | Bruenke et al. A recombinant bispecific single-chain Fv antibody against HLA class II and FcgammaRIII (CD16) triggers effective lysis of lymphoma cells. Br J Haematol. 2004 Apr; 125(2):167-79. PMID:15059139 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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