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Antigenic Specificity | RIT1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total RIT1 protein. Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation.Manabu Furukawa, Mol. Cell. Biol., Nov 2000; 20: 8185 - 8197. Angus Chen, J. Biol. Chem., May 2000; 275: 15432. Kenneth Wu, Mol. Cell. Biol., Feb 2000; 20: 1382 - 1393. Kenneth Wu, J. Biol. Chem., Jan 2002; 277: 516 - 527. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human RIT1. |
Other Names | [GTP-binding protein Rit1; Ras-like protein expressed in many tissues; Ras-like without CAAX protein 1; RIBB; RIT] |
Gene, Accession # | [RIT1], Gene ID: 6016, NCBI: NP_001243749.1, UniProt: Q92963 |
Catalog # | MBS9402178 |
Price | $200, $255 |
Order / More Info | RIT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |