RIT1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRIT1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of total RIT1 protein. Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation.Manabu Furukawa, Mol. Cell. Biol., Nov 2000; 20: 8185 - 8197. Angus Chen, J. Biol. Chem., May 2000; 275: 15432. Kenneth Wu, Mol. Cell. Biol., Feb 2000; 20: 1382 - 1393. Kenneth Wu, J. Biol. Chem., Jan 2002; 277: 516 - 527.
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human RIT1.
Other Names[GTP-binding protein Rit1; Ras-like protein expressed in many tissues; Ras-like without CAAX protein 1; RIBB; RIT]
Gene, Accession #[RIT1], Gene ID: 6016, NCBI: NP_001243749.1, UniProt: Q92963
Catalog #MBS9402178
Price$200, $255
Order / More InfoRIT1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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