CALCOCO2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CALCOCO2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunoflouresence/Immunocytochemistry (IF/ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CALCOCO2 antibody detects endogenous levels of CALCOCO2. Function: Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation. Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens such as Salmonella typhimurium upon entry into the cytosol by targeting LGALS8-associated bacteria for autophagy (PubMed:22246324). Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen-containing autophagosome maturation (PubMed:23022382, PubMed:25771791). Bacteria targeting to autophagosomes relies on its interaction with MAP1LC3A, MAP1LC3B and/or GABARAPL2, whereas regulatio |
| Immunogen | Immunogen: A synthesized peptide derived from human CALCOCO2. |
| Other Names | [calcium-binding and coiled-coil domain-containing protein 2 isoform 1; Calcium-binding and coiled-coil domain-containing protein 2; calcium-binding and coiled-coil domain-containing protein 2; calcium binding and coiled-coil domain 2; Antigen nuclear dot 52 kDa protein; Nuclear domain 10 protein NDP52] |
| Gene, Accession # | [CALCOCO2], Gene ID: 10241, NCBI: NP_001248319.1, UniProt: Q13137 |
| Catalog # | MBS9603588 |
| Price | $240, $280 |
| Order / More Info | CALCOCO2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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