Phospho-DDR1 (Tyr520) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-DDR1 (Tyr520)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, ratpredicted: horse, sheep, rabbit
Isotypen/a
Formatpeptide affinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Peptide ELISA (EIA)
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DescriptionSpecificity: Phospho-DDR1 (Tyr520) Antibody detects endogenous levels of DDR1 only when phosphorylated at Tyr520. Description: Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differ
ImmunogenImmunogen: A synthesized peptide derived from human DDR1 around the phosphorylation site of Tyr520. Tissue Specificity: Detected in T-47D, MDA-MB-175 and HBL-100 breast carcinoma cells, A-431 epidermoid carcinoma cells, SW48 and SNU-C2B colon carcinoma cells and Hs 294T melanoma cells (at protein level). Expressed at low levels in most adult tissues and is highest in the brain, lung, placenta and kidney. Lower levels of expression are detected in melanocytes, heart, liver, skeletal muscle and pa
Other Names[CAK; CD 167; CD167; CD167 antigen-like family member A; CD167a; Cell adhesion kinase; DDR 1; DDR; DDR1; DDR1_HUMAN; Discoidin domain receptor; Discoidin domain receptor tyrosine kinase 1; Discoidin receptor tyrosine kinase; Discoidin receptor tyrosine kinase isoform a; EDDR 1; EDDR1; Epithelial discoidin domain receptor 1; Epithelial discoidin domain-containing receptor 1; Epithelial specific receptor kinase; HGK2; Mammarian carcinoma kinase 10; Mammary carcinoma kinase 10; MCK-10; MCK10; NEP; Neuroepithelial tyrosine kinase; Neurotrophic tyrosine kinase receptor type 4; NTRK 4; NTRK4; OTTHUMP00000029343; OTTHUMP00000029344; OTTHUMP00000029345; OTTHUMP00000029346; OTTHUMP00000029347; OTTHUMP00000164863; OTTHUMP00000164867; OTTHUMP00000222080; Protein-tyrosine kinase 3A; Protein-tyrosine kinase RTK-6; PTK 3; PTK 3A protein tyrosine kinase 3A; PTK3; PTK3A; Receptor tyrosine kinase NEP; RTK 6; RTK6; TRK E; TRKE; Tyrosine kinase DDR; Tyrosine kinase receptor E; Tyrosine-protein kinase CAK]
Gene, Accession #[DDR1], Gene ID: 780, NCBI: NP_001189450.1, UniProt: Q08345
Catalog #MBS9610723
Price$225, $280, $340
Order / More InfoPhospho-DDR1 (Tyr520) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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