OPTN (Center), 71-96 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | OPTN (Center), 71-96 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: rat) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This OPTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-96 amino acids from the Central region of human OPTN. This gene encodes the coiled-coil containing proteinoptineurin. Optineurin may play a role in normal-tension glaucomaand adult-onset primary open angle glaucoma. Optineurin interactswith adenovirus E3-14.7K protein and may utilize tumor necrosisfactor-alpha or Fas-ligand pathways to mediate apoptosis,inflammation or vasoconstriction. Optineurin may also function incellular morphogenesis and membrane trafficking, vesicletrafficking, and transcription activation through its interactionswith the RAB8, huntingtin, and transcription factor IIIA proteins. |
| Immunogen | n/a |
| Other Names | [Optineurin; E3-147K-interacting protein; FIP-2; Huntingtin yeast partner L; Huntingtin-interacting protein 7; HIP-7; Huntingtin-interacting protein L; NEMO-related protein; Optic neuropathy-inducing protein; Transcription factor IIIA-interacting protein; TFIIIA-IntP; OPTN; FIP2; GLC1E; HIP7; HYPL; NRP] |
| Gene, Accession # | [OPTN], Gene ID: 10133, NCBI: NP_001008212.1, UniProt: Q96CV9 |
| Catalog # | MBS9211251 |
| Price | $165, $370 |
| Order / More Info | OPTN (Center), 71-96 Antibody from MYBIOSOURCE INC. |
| Product Specific References | McDonald, K.K., et al. J. Hum. Genet. 55(10):697-700(2010) Cheng, J.W., et al. Med. Sci. Monit. 16 (8), CR369-CR377 (2010) : Albagha, O.M., et al. Nat. Genet. 42(6):520-524(2010) Maruyama, H., et al. Nature 465(7295):223-226(2010) Park, B., et al. PLoS ONE 5 (7), E11547 (2010) : |
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