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Antigenic Specificity | beta Catenin Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Catenins are proteins found in complexes with cadherin cell adhesion molecules of animal cells. The first two catenins that were identified became known as alpha-catenin and beta-catenin. Alpha-catenin can bind to beta-catenin and can also bind actin. Beta-catenin binds the cytoplasmic domain of some cadherins. Beta-catenin is an adherens junction protein. It plays an important role in various aspects of liver biology including liver development (both embryonic and postnatal), liver regeneration following partial hepatectomy. HGF-induced hepatpomegaly, liver zonation, and pathogenesis of liver cancer.Protein Function: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex wit |
Immunogen | Immunogen: E Coli-derived human beta Catenin recombinant protein (Position: A2-K233). Subcellular Localization: Cytoplasm. Nucleus Tissue Specificity: Expressed in several hair follicle cell types: basal and peripheral matrix cells, and cells of the outer and inner root sheaths. Expressed in colon. Present in cortical neurons (at protein level). |
Other Names | [Catenin beta-1; Beta-catenin; CTNNB1; CTNNB; OK/SW-cl.35; PRO2286] |
Gene, Accession # | [CTNNB1], Gene ID: 1499, NCBI: P35222.1, UniProt: P35222 |
Catalog # | MBS1750301 |
Price | $315 |
Order / More Info | beta Catenin Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |