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Antigenic Specificity | Phospho-GSK3 alpha/beta (Tyr279/216) |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-GSK3 alpha/beta (Tyr279/216) Antibody detects endogenous levels of GSK3 alpha/beta only when phosphorylated at Tyrosine 279/216. GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase. |
Immunogen | Immunogen: A synthesized peptide derived from human GSK3 alpha/beta around the phosphorylation site of Tyrosine 279/216 |
Other Names | [DKFZp686D0638; glycogen synthase kinase 3 alpha; Glycogen synthase kinase-3 alpha; GSK-3 alpha; GSK3A] |
Gene, Accession # | [GSK3 alpha/beta], Gene ID: 2931, NCBI: NP_063937.2, UniProt: P49840 |
Catalog # | MBS8511516 |
Price | $290 |
Order / More Info | Phospho-GSK3 alpha/beta (Tyr279/216) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |