GRK5 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-GRK5 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | GRK5 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total GRK5 protein. Serine/threonine kinase that phosphorylates preferentially the activated forms of a variety of G-protein-coupled receptors (GPCRs). Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their down-regulation. Phosphorylates a variety of GPCRs, including adrenergic receptors, muscarinic acetylcholine receptors (more specifically Gi-coupled M2/M4 subtypes), dopamine receptors and opioid receptors. In addition to GPCRs, also phosphorylates various substrates: Hsc70-interacting protein/ST13, TP53/p53, HDAC5, and arrestin-1/ARRB1. Phosphorylation of ARRB1 by GRK5 inhibits G-protein independent MAPK1/MA |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human GRK5. |
| Other Names | [EC 2.7.11.16; G-protein-coupled receptor kinase 5; GPRK5; kinase GRK5] |
| Gene, Accession # | [GRK5], Gene ID: 2869, NCBI: NP_005299.1, UniProt: P34947 |
| Catalog # | MBS9407858 |
| Price | $200, $255 |
| Order / More Info | GRK5 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies