Edit |   |
---|---|
Antigenic Specificity | p53 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The p53 gene like the Rb gene, is a tumor suppressor gene, i.e., its activity stops the formation of tumors. If a person inherits only one functional copy of the p53 gene from their parents, they are predisposed to cancer and usually develop several independent tumors in a variety of tissues in early adulthood. This condition is rare, and is known as Li-Fraumeni syndrome. However, mutations in p53 are found in most tumor types, and so contribute to the complex network of molecular events leading to tumor formation. |
Immunogen | Immunogen: p53 antibody was raised in Rabbit using the peptide sequence around phosphorylation site of serine 6 (P-Q-S(p)-D-P) derived from Human p53 as the immunogen. |
Other Names | [Rabbit p53; p53; p53; p53; p 53; p-53; p 53; p-53; Phospho Ser6; p53 Oncoprotein; transformation-related protein 53; trp53; tumor protein 53; tumor protein p53 (Li-Fraumeni syndrome); tumor suppressing protein; tumor suppressor homolog p53; Tumor suppressor p53; tumor suppressor protein; tumor suppressor protein p53; tumor suppressor TP53; tumor supressor p53; Xp53] |
Gene, Accession # | [p53], Gene ID: 7157, NCBI: BAC16799.1 |
Catalog # | MBS5309510 |
Price | $295 |
Order / More Info | p53 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |