PPM1D Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PPM1D |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: PPM1D antibody is human, mouse and rat reactive. At least two isoforms of PPM1D are known to exist; this antibody will only detect the larger isoform. Wild-type p53 induced phosphatase 1 (WIP1) / protein phosphatase magnesium-dependent 1 delta (PPM1D), a protein identified in the p53 DNA response pathway, is a member of the PP2C family of serine/threonine protein phosphatases which selectively inactivates p38 MAPK and dephosphorylates the ATM/ATR targets, Chk1 and p53 (1,2). Studies have shown that it is overexpressed in human cancers and is involved in the regulation of multiple DNA damage signaling pathways (2,3). PPM1D deletion results in a reduction of T and B cell function and compromised cell division, rendering cells res |
| Immunogen | Immunogen: PPM1D antibody was raised against an 18 amino acid peptide near the carboxy terminus of human PPM1D. Buffer: PPM1D antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [Protein phosphatase Mg2+/Mn2+ dependent 1D; p53-induced protein phosphatase 1; PP2C-DELTA; Protein phosphatase 1D; WIP1; Protein phosphatase Mg2+/Mn2+ dependent 1D], [PPM1D; PPM1D; WIP1; PP2C-DELTA; WIP1; PP2C-delta] |
| Gene, Accession # | [PPM1D], Gene ID: 8493, NCBI: NP_003611, UniProt: Q8IVR6 |
| Catalog # | MBS153719 |
| Price | $375 |
| Order / More Info | PPM1D Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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