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Antigenic Specificity | ABCG2 (CD338) |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total ABCG2(CD338) protein. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123. |
Immunogen | Immunogen: Peptide sequence around aa.160~164(R-I-N-R-V) derived from Human ABCG2(CD338). |
Other Names | [BMDP; MRX; ABC15; ABCP; BCRP1] |
Gene, Accession # | [ABCG2], Gene ID: 9429, NCBI: NP_001244315.1, UniProt: Q9UNQ0 |
Catalog # | MBS8511690 |
Price | $290 |
Order / More Info | ABCG2 (CD338) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |