UBE2O Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityUBE2O
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatfluorescein (FITC) conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionE2/E3 hybrid ubiquitin-protein ligase that displays both E2 and E3 ligase activities and mediates monoubiquitination of target proteins (PubMed:23455153, PubMed:24703950). Negatively regulates TRAF6-mediated NF-kappa-B activation independently of its E2 activity (PubMed:23381138). Acts as a positive regulator of BMP7 signaling by mediating monoubiquitination of SMAD6, thereby regulating adipogenesis (PubMed:23455153). Mediates monoubiquitination at different sites of the nuclear localization signal (NLS) of BAP1, leading to cytoplasmic retention of BAP1. Also able to monoubiquitinate the NLS of other chromatin-associated proteins, such as INO80 and CXXC1, affecting their subcellular location (PubMed:24703950). Acts as a regulator of retrogr
ImmunogenImmunogen: Recombinant human (E3-independent) E2 ubiquitin-conjugating enzyme protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-109125
Other Names[(E3-independent) E2 ubiquitin-conjugating enzyme (EC:2.3.2.242 Publications; UBE2O; KIAA1734; E2/E3 hybrid ubiquitin-protein ligase UBE2O; Ubiquitin carrier protein O; Ubiquitin-conjugating enzyme E2 O; Ubiquitin-conjugating enzyme E2 of 230 kDa; Ubiquitin-conjugating enzyme E2-230K; Ubiquitin-protein ligase O], [UBE2O; UBE2O; E2-230K; KIAA1734; Ubiquitin-conjugating enzyme E2-230K]
Gene, Accession #[UBE2O], Gene ID: 63893, NCBI: NP_071349.3, UniProt: Q9C0C9
Catalog #MBS1494824
Price$160, $235
Order / More InfoUBE2O Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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