Calcitonin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCalcitonin
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat.
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Paraffin
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DescriptionRabbit IgG polyclonal antibody for Calcitonin gene-related peptide 1 (CALCA) detection. Background: Calcitonin, also known as CALCA, is a peptide hormone synthesized by the parafollicular cells of the thyroid. It is mapped to 11p15.2. Calcitonin belongs to the calcitonin-like protein family. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Calcitonin (83-119aa SCNTATCVTHRLAGLLSRSGGVVKDNFVPTNVGSEAF), different from the related human sequence by four amino acids, and identical to the related rat sequence.
Other Names[Alpha CGRP; alpha type CGRP; CALC1; CALC 1; CALC A; CALCA; calcitonin1; calcitonin-1; calcitonin 1; CGRP1; CGRP 1; CGRP-1 |CT; katacalcin; KC; Q99JA0; Calcitonin gene-related peptide 1; calcitonin related polypeptide alpha], [Calca; Calca; CA; Ct; Ctn; Calc; Cgrp; CGRP1; Calc1; CGRP-1; Calc; CGRP-I]
Gene, Accession #[CALCA], Gene ID: 12310, NCBI: NP_001029126.1, UniProt: Q99JA0
Catalog #MBS178437
Price$315
Order / More InfoCalcitonin Antibody from MYBIOSOURCE INC.
Product Specific References1. Alevizaki, M., Stevenson, J. C., Girgis, S. I., MacIntyre, I., Legon, S. Altered calcitonin gene in a young patient with osteoporosis.Brit. Med. J. 298: 1215-1216, 1989. Note: Retraction: Brit. Med. J. 299: 235 only, 1989.2. Breimer, L. H., MacIntyre, I., Zaidi, M. Peptides from the calcitonin genes: molecular genetics, structure and function. Biochem. J. 255: 377-390, 1988.3. Edbrooke, M. R., Parker, D., McVey, J. H., Riley, J. H., Sorenson, G. D., Pettengill, O. S., Craig, R. K. Expression of the human calcitonin/CGRP gene in lung and thyroid carcinoma. EMBO J. 4: 715-724, 1985.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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