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Antigenic Specificity | Calcitonin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat. |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for Calcitonin gene-related peptide 1 (CALCA) detection. Background: Calcitonin, also known as CALCA, is a peptide hormone synthesized by the parafollicular cells of the thyroid. It is mapped to 11p15.2. Calcitonin belongs to the calcitonin-like protein family. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Calcitonin (83-119aa SCNTATCVTHRLAGLLSRSGGVVKDNFVPTNVGSEAF), different from the related human sequence by four amino acids, and identical to the related rat sequence. |
Other Names | [Alpha CGRP; alpha type CGRP; CALC1; CALC 1; CALC A; CALCA; calcitonin1; calcitonin-1; calcitonin 1; CGRP1; CGRP 1; CGRP-1 |CT; katacalcin; KC; Q99JA0; Calcitonin gene-related peptide 1; calcitonin related polypeptide alpha], [Calca; Calca; CA; Ct; Ctn; Calc; Cgrp; CGRP1; Calc1; CGRP-1; Calc; CGRP-I] |
Gene, Accession # | [CALCA], Gene ID: 12310, NCBI: NP_001029126.1, UniProt: Q99JA0 |
Catalog # | MBS178437 |
Price | $315 |
Order / More Info | Calcitonin Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Alevizaki, M., Stevenson, J. C., Girgis, S. I., MacIntyre, I., Legon, S. Altered calcitonin gene in a young patient with osteoporosis.Brit. Med. J. 298: 1215-1216, 1989. Note: Retraction: Brit. Med. J. 299: 235 only, 1989.2. Breimer, L. H., MacIntyre, I., Zaidi, M. Peptides from the calcitonin genes: molecular genetics, structure and function. Biochem. J. 255: 377-390, 1988.3. Edbrooke, M. R., Parker, D., McVey, J. H., Riley, J. H., Sorenson, G. D., Pettengill, O. S., Craig, R. K. Expression of the human calcitonin/CGRP gene in lung and thyroid carcinoma. EMBO J. 4: 715-724, 1985. |