Human PD-1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human PD-1 |
| Clone | [9X21] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2 |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Neutralization (N) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Programmed Death1 (PD1) is a type I transmembrane protein belonging to the CD28/CTLA4 family of immunoreceptors that mediate signals for regulating immune responses. Members of the CD28/CTLA4 family have been shown to either promote T cell activation (CD28 and ICOS) or downregulate T cell activation (CTLA4 and PD1). PD1 is expressed on activated T cells, B cells, myeloid cells, and on a subset of thymocytes. In vitro, ligation of PD1 inhibits TCRmediated T cell proliferation and production of IL1, IL4, IL10, and IFNgamma. In addition, PD1 ligation also inhibits BCR mediated signaling. PD1 deficient mice have a defect in peripheral tolerance and spontaneously develop autoimmune diseases. Two B7 family proteins, PDL1 (also called B7H1) and PD |
| Immunogen | Preparation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human PD-1. Antigen: Recombinant human PD-1. Remarks: This antibody was selected for its ability to detect specifically human PD-1 |
| Other Names | [PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l], [PDCD1; PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; PD1; Protein PD-1; hPD-1] |
| Gene, Accession # | [PD-1], Gene ID: 5133, NCBI: NP_005009.2, UniProt: Q15116 |
| Catalog # | MBS690864 |
| Price | $490 |
| Order / More Info | Human PD-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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