(Mouse) Rnf2 (Center) Antibody from MYBIOSOURCE INC.

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Antigenic Specificity(Mouse) Rnf2 (Center)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatunconjugated
Size0.08 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis Mouse Rnf2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 198-232 amino acids from the Central region of Mouse Rnf2. E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), thereby playing a central role in histone code and gene regulation. H2AK119Ub gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. May be involved in the initiation of both imprinted and random X inactivation. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, thro
Immunogenn/a
Other Names[Purified Rabbit (Pab); E3 ubiquitin-protein ligase RING2, 632-; RING finger protein 1B; RING1b; RING finger protein 2; Rnf2; DinG; Ring1b]
Gene, Accession #[Rnf2], Gene ID: 19821, NCBI: NP_035407.1, UniProt: Q9CQJ4
Catalog #MBS9216259
Price$150
Order / More Info(Mouse) Rnf2 (Center) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSchoorlemmer J.,et al.EMBO J. 16:5930-5942(1997).Carninci P.,et al.Science 309:1559-1563(2005).Ebert L.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.Garcia E.,et al.EMBO J. 18:3404-3418(1999).Suzuki M.,et al.Development 129:4171-4183(2002).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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