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Antigenic Specificity | H3f3b (C-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This H3f3b antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 103-136 amino acids from mouse H3f3b. Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DN |
Immunogen | n/a |
Other Names | [Purified Rabbit (Pab); Histone H33; H3f3a; H33a] |
Gene, Accession # | [H3f3a], Gene ID: 15078, NCBI: NP_032236.1, UniProt: P84244 |
Catalog # | MBS9216046 |
Price | $165, $370 |
Order / More Info | H3f3b (C-Term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Hraba-Renevey S.,et al.Nucleic Acids Res. 17:2449-2461(1989).Bramlage B.,et al.Differentiation 62:13-20(1997).Lopez-Alanon D.M.,et al.DNA Cell Biol. 16:639-644(1997).Carninci P.,et al.Science 309:1559-1563(2005).Mancini P.,et al.J. Mol. Evol. 59:458-463(2004). |