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Antigenic Specificity | Human E-Selectin |
Clone | [9E7] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2 |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) - Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes human E-selectin in western blot. Reactivity to ESelectin of other species is not tested. No cross reactivity to ICAM, and VCAM. E-Selectin (Endothelial Leukocyte Adhesion Molecule1, ELAM1, CD62E), a member of the Selectin family, is a 107-115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response to IL 1beta and TNFalpha, and demonstrates peak expression at 4 hours, and decay at 24 hours, in response to activation. E-Selectin ligands, expressed on neutrophils, monocytes, and a subset of memory T cells, are sialylated, fucosylated molecules which bind to the lectin domain of E-Selectin. Immunocytochemical techniques have demonstrated the expression of E-Selectin on healt |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with purified human recombinant E-selectin protein. The IgG2 fraction of the tissue culture supernatant was purified by Protein G affinity chromatography. |
Other Names | [human E-Selectin], [SELE; SELE; ELAM; ESEL; CD62E; ELAM1; LECAM2; ELAM1; ELAM-1; LECAM2] |
Gene, Accession # | Gene ID: 6401, NCBI: NP_000441.2, UniProt: P16581 |
Catalog # | MBS690867 |
Price | $490 |
Order / More Info | Human E-Selectin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |