Integrin alpha3 (CD49c) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Integrin alpha3 (CD49c) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Integrin alpha3 (CD49c) antibody detects endogenous levels of total Integrin alpha3 (CD49c). Function: Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.Subunit Structure: Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of a heavy and a light chain linked by a disulfide bond. Alpha-3 associates |
| Immunogen | Immunogen: A synthesized peptide derived from human Integrin alpha3 (CD49c) Subcellular Location: Membrane. Tissue Specificity: Isoform 1 is widely expressed. Isoform 2 is expressed in brain and heart. In brain, both isoforms are exclusively expressed on vascular smooth muscle cells, whereas in heart isoform 1 is strongly expressed on vascular smooth muscle cells, isoform 2 is detected only on endothelial vein cells. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: |
| Other Names | [AA407068; Antigen identified by J143; CD49 antigen like family member C; CD49 antigen-like family member C; CD49c; CD49c antigen; FLJ34631; FLJ34704; FRP 2; FRP-2; FRP2; Galactoprotein B3; GAP B3; GAPB3; Integrin alpha 3; Integrin alpha-3 light chain; Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor); ITA3_HUMAN; ITGA 3; Itga3; MSK18; VCA 2; VCA2; Very late activation protein 3 receptor alpha 3 subunit; VL3A; VLA 3 alpha chain; VLA 3 subunit alpha; VLA-3 subunit alpha; VLA3a] |
| Gene, Accession # | [ITGA3], Gene ID: 3675, NCBI: NP_002195.1, UniProt: P26006 |
| Catalog # | MBS9601355 |
| Price | $240, $280 |
| Order / More Info | Integrin alpha3 (CD49c) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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