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Antigenic Specificity | MSK1 (Ser360) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | humanpredicted: chicken, mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MSK1 (Ser360) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 330-363 amino acids from the human MSK1 (Ser360). Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. Plays an essential role in the control of RELA transcriptional activity in response to TNF and upo |
Immunogen | n/a |
Other Names | [Ribosomal protein S6 kinase alpha-5; S6K-alpha-5; 2.7.11.1; 90 kDa ribosomal protein S6 kinase 5; Nuclear mitogen-and stress-activated protein kinase 1; RSK-like protein kinase; RSKL; RPS6KA5; MSK1] |
Gene, Accession # | [MSK1], Gene ID: 9252, NCBI: NP_001309164.1, UniProt: O75582 |
Catalog # | MBS9231029 |
Price | $165, $370 |
Order / More Info | MSK1 (Ser360) Antibody from MYBIOSOURCE INC. |
Product Specific References | Deak M.,et al.EMBO J. 17:4426-4441 (1998). New L.,et al.J. Biol. Chem. 274:1026-1032 (1999). Jiang C.,et al.Cytogenet. Cell Genet. 87:261-262 (1999). Ota T.,et al.Nat. Genet. 36:40-45 (2004). Heilig R.,et al.Nature 421:601-607 (2003). |