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Antigenic Specificity | Collagen XVII |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Collagen XVII antibody detects endogenous levels of total Collagen XVII. Function: May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane.Subunit Structure: Homotrimers of alpha 1(XVII)chains. Interacts (via cytoplasmic region) with ITGB4 (via cytoplasmic region). Interacts (via cytoplasmic region) with DST isoform 3 (via N-terminus). Interacts (via N-terminus) with PLEC. Interacts (via cytoplasmic region) with DSP.Post-translational Modifications: The intracellular/endo domain is disulfide-linked. Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. The ectodomain is shedded from th |
Immunogen | Immunogen: A synthesized peptide derived from human Collagen XVII Subcellular Location: Cell Junction, Hemidesmosome. Membrane; Single-Pass Type II Membrane Protein. Note=Localized along the plasma membrane of the hemidesmosome. 120 kDa linear IgA disease antigen and 97 kDa linear IgA disease antigen: Secreted, extracellular space, extracellular matrix, basement membrane. Tissue Specificity: Detected in skin (PubMed:8618013). In the cornea, it is detected in the epithelial basement membrane, the |
Other Names | [180 kDa bullous pemphigoid antigen 2; Alpha 1 type XVII collagen; BA16H23.2; BP 180; BP180; BPA 2; BPAG 2; BPAG2; Bullous pemphigoid antigen 2; COL17A1; Collagen 17; Collagen alpha 1 XVII chain; Collagen alpha 1(XVII) chain; Collagen alpha1 XVII chain; Collagen type XVII alpha 1; Collagen XVII alpha 1 polypeptide; CollagenXVII; Epidermolysis bullosa junctional localisata variant; FLJ60881; KIAA0204; LAD 1; LAD1] |
Gene, Accession # | [COL17A1], Gene ID: 1308, NCBI: NP_000485.3, UniProt: Q9UMD9 |
Catalog # | MBS9604387 |
Price | $240, $280 |
Order / More Info | Collagen XVII Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |