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Antigenic Specificity | CSTB (Center), 10-39 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CSTB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the Central region of human CSTB. The cystatin superfamily encompasses proteins that containmultiple cystatin-like sequences. Some of the members are activecysteine protease inhibitors, while others have lost or perhapsnever acquired this inhibitory activity. There are three inhibitoryfamilies in the superfamily, including the type 1 cystatins(stefins), type 2 cystatins and kininogens. This gene encodes astefin that functions as an intracellular thiol protease inhibitor.The protein is able to form a dimer stabilized by noncovalentforces, inhibiting papain and cathepsins l, h and b. The |
Immunogen | n/a |
Other Names | [Cystatin-B; CPI-B; Liver thiol proteinase inhibitor; Stefin-B; CSTB; CST6; STFB] |
Gene, Accession # | [CSTB], Gene ID: 1476, NCBI: NP_000091.1, UniProt: P04080 |
Catalog # | MBS9203846 |
Price | $165, $370 |
Order / More Info | CSTB (Center), 10-39 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Ceru, S., et al. J. Biol. Chem. 285(13):10078-10086(2010) Skerget, K., et al. J. Biol. Chem. 285(5):3201-3210(2010) Ceru, S., et al. Biol. Cell 102(6):319-334(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) |