Phospho-c-Jun (pSer63) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-c-Jun (pSer63)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat, mouse, bovine. dog
Isotypen/a
Formatepitope affinity purified
Size0.1 mg
ConcentrationSize: 100 ug/200 ul
ApplicationsELISA, Western Blot, Immunohistochemistry
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DescriptionThis antibody recognizes ~48 kDa of human c-Jun protein. It does not recognize non-phosphorylated peptides. This antibody also reacts with mouse and rat. The other species are not tested. c-Jun, also known as AP1, v-Jun or AH119, is a component of the transcription factor AP-1, which binds and activates transcription at TRE/AP-1 elements. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73 as well as Thr 91 and Thr93. Extracellular signals including growth factors, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun-dependent transcription. The MAP kinase homologue SAPK/JNK binds to the amino-terminal region of c-Jun and phosphorylates c-Jun at S
ImmunogenAntigen Preparation: A synthetic peptide corresponding to the epitope -LTSPD- at a phosphorylation site at serine 63 of human c-Jun protein. This sequence is identical within human, rat, mouse, bovine and dog.
Other Names[Rabbit c-Jun (pS63); Transcription factor c-Jun; v-Jun sarcoma virus 17-oncogene; JUN/AP1; AH119], [C-JUN; JUN; Jun]
Gene, Accession #[c-Jun (pS63)], Gene ID: 396913, UniProt: P56432
Catalog #MBS462029
Price$285
Order / More InfoPhospho-c-Jun (pSer63) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesYuanbin Xie, et al. Indirubin-3?-oxime inhibits c-Jun NH2-terminal kinase: anti-apoptotic effect in cerebellar granule neurons (2004) Neuroscience Letters, 367 (3), 355-359.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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