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Antigenic Specificity | Phospho-c-Jun (pSer63) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse, bovine. dog |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | Size: 100 ug/200 ul |
Applications | ELISA, Western Blot, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes ~48 kDa of human c-Jun protein. It does not recognize non-phosphorylated peptides. This antibody also reacts with mouse and rat. The other species are not tested. c-Jun, also known as AP1, v-Jun or AH119, is a component of the transcription factor AP-1, which binds and activates transcription at TRE/AP-1 elements. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73 as well as Thr 91 and Thr93. Extracellular signals including growth factors, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun-dependent transcription. The MAP kinase homologue SAPK/JNK binds to the amino-terminal region of c-Jun and phosphorylates c-Jun at S |
Immunogen | Antigen Preparation: A synthetic peptide corresponding to the epitope -LTSPD- at a phosphorylation site at serine 63 of human c-Jun protein. This sequence is identical within human, rat, mouse, bovine and dog. |
Other Names | [Rabbit c-Jun (pS63); Transcription factor c-Jun; v-Jun sarcoma virus 17-oncogene; JUN/AP1; AH119], [C-JUN; JUN; Jun] |
Gene, Accession # | [c-Jun (pS63)], Gene ID: 396913, UniProt: P56432 |
Catalog # | MBS462029 |
Price | $285 |
Order / More Info | Phospho-c-Jun (pSer63) Antibody from MYBIOSOURCE INC. |
Product Specific References | Yuanbin Xie, et al. Indirubin-3?-oxime inhibits c-Jun NH2-terminal kinase: anti-apoptotic effect in cerebellar granule neurons (2004) Neuroscience Letters, 367 (3), 355-359. |