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Antigenic Specificity | S22A2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of S22A2 protein. Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specific |
Immunogen | Immunogen: Synthesized peptide derived from part region of human S22A2 protein |
Other Names | [Rabbit S22A2; Solute carrier family 22 member 2; Organic cation transporter 2; hOCT2] |
Gene, Accession # | [S22A2], Gene ID: 6582, NCBI: NP_003049.2, UniProt: O15244 |
Catalog # | MBS9710830 |
Price | $130, $220, $325 |
Order / More Info | S22A2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |