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Antigenic Specificity | CREB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcription factor CREB binds the cAMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth or neurotrophic factors. Protein kinase A and the calmodulin dependent protein kinase CamonkeyII stimulate CREB phosphorylation at Ser133, a key regulatory site controlling transcriptional activity. Phosphorylation at Ser133 is also mediated by p44/42 MAP kinase, p90RSK, p38 MAP kinase and MSK1. CREB appears to play an important role in learning and memory in both flies and mice. |
Immunogen | Immunogen: CREB antibody was raised in Rabbit using synthetic peptide surrounding amino acid 109 of rat CREB as the immunogen. |
Other Names | [Rabbit CREB; CREB; CREB] |
Gene, Accession # | [CREB], Gene ID: 11833537, NCBI: AEV65390.1 |
Catalog # | MBS5309092 |
Price | $705 |
Order / More Info | CREB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |