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Antigenic Specificity | rat Kininogen-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a card |
Immunogen | Immunogen: Recombinant rat Kininogen-1 protein(2-110AA) |
Other Names | [Kng], [Kng2; Kng1; Kng1; Kngk; KINKG; KINKH; Kng] |
Gene, Accession # | [Kng1], Gene ID: 25087, NCBI: NP_036873.1, UniProt: P08934 |
Catalog # | MBS1493338 |
Price | $160, $235 |
Order / More Info | rat Kininogen-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |