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Antigenic Specificity | PRMT5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PRMT5 antibody detects endogenous levels of total PRMT5. Description: Human Skb1Hs methyltransferase (also called JBP1), a homologue of yeast protein Skb1 and Hsl7p (1, 2), is composed of 637 amino acid residues and contains motifs conserved among protein methyltransferases. It methylates histones and MBP in vitro (2). Yeast Hsl7p is involved in regulation of cell cycle progression through G2 by negatively regulating Swe1p, a protein tyrosine kinase that phosphorylates and inhibits Cdc28p (3). An Hsl7p homologue, Skb1, was identified in fission yeast by virtue of its yeast two-hybrid interaction with Shk1p, a p21 (cdc42p/Rac) activated kinase (PAK) (4). Both proteins belong to the protein methyltransferase superfamily (5). Inte |
Immunogen | Immunogen: A synthetic peptide of human PRMT5 Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Ubiquitous. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Xenopus (100%) |
Other Names | [72 kDa ICln binding protein; 72 kDa ICln-binding protein; ANM5_HUMAN; Histone synthetic lethal 7, S. cerevisiae, homolog of; Histone-arginine N-methyltransferase PRMT5; HMT1 hnRNP methyltransferase like 5; HOMOLOG OF; SKB1; HRMT1L5; IBP72; Jak-binding protein 1; JBP 1; JBP1; PRMT 5; PRMT5; Protein arginine methyltransferase 5; Protein arginine N methyltransferase 5; Protein arginine N methyltransferase 5 N terminally processed; Protein arginine N-methyltransferase 5; S. POMBE; S. POMBE HOMOLOG OF; SKB1; SHK1 KINASE BINDING PROTEIN 1; Shk1 kinase binding protein 1 homolog; Shk1 kinase-binding protein 1 homolog; Shk1 kinase/binding protein 1, S. pombe, homolog of; SKB 1; SKB1; SKB1 homolog; SKB1: SKB1 homolog (S. pombe); SKB1Hs] |
Gene, Accession # | [PRMT5], Gene ID: 10419, NCBI: NP_001034708.1, UniProt: O14744 |
Catalog # | MBS9607096 |
Price | $240, $280 |
Order / More Info | PRMT5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |