CYR61 (Center) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | CYR61 (Center) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This CYR61 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 143-174 amino acids from the Central region of human CYR61. Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up- regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration thro |
| Immunogen | n/a |
| Other Names | [Purified Rabbit (Pab); Protein CYR61; CCN family member 1; Cysteine-rich angiogenic inducer 61; Insulin-like growth factor-binding protein 10; IBP-10; IGF-binding protein 10; IGFBP-10; Protein GIG1; CYR61; CCN1; GIG1; IGFBP10] |
| Gene, Accession # | [CYR61], Gene ID: 3491, NCBI: NP_001545.2, UniProt: O00622 |
| Catalog # | MBS9216353 |
| Price | $165, $370 |
| Order / More Info | CYR61 (Center) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Jay P.,et al.Oncogene 14:1753-1757(1997).Martinerie C.,et al.Mol. Pathol. 50:310-316(1997).Albrecht C.,et al.J. Biol. Chem. 275:28929-28936(2000).Kolesnikova T.V.,et al.Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases.Bi A.B.,et al.Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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